Pentedrone

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It goes by the systematic and formal IUPAC name (RS)-1-phenyl-2-(methylamino)pentan-1-one. Pentedrone hydrochloride forms a white powder at room temperature and pressure. It has a molar mass of 191.27 grams and molecular formula C12H17NO. The hydrochloride salt has a melting point of 176.8 oC and molar mass of 227.73 grams.

The chemical exerts its stimulant effect by acting as a noradrenaline-dopamine reuptake inhibitor. It does not cause the release of these neurochemicals. This pharmacological action is similar to methylphenidate.

Such up-regulation is a sign of over stimulation of the dopaminergic pathway, and is a key homeostatic action of the body to self regulate.

This result is a demonstration of its rewarding properties.. Acute administration of pentedrone in rats increases locomotor activity in a dose dependent manner.

The toxicological profile of pentedrone in humans is unknown. The health effects of long term and even short term recreational use have not been investigated.

The chemical is not for human or animal consumption.

Unverifiable online reports give us some indication of the effects of this compound.

It is said to produce feelings of euphoria, mental and physical stimulation, increased focus, mental clarity and increased productivity.

Neutral reported effects include loss of appetite and some distortions in the visual field.

Pentedrone, if consumed at high doses or for prolonged periods of time, can induce psychosis. This is a phenomenon known as stimulant psychosis. Symptoms include hallucinations, delusions and disordered thinking.

The individual died from heart failure.

It is dangerous to combine pentedrone with Tramadol as this may increase the risk of seizure. People taking prescription MAOI antidepressants should avoid pentedrone and other stimulants as this combination may result in a hypertensive crisis.

It is unsafe to combine with DXM as both compounds increase heart rate.

Other names and synonyms:

Pentanone, 2-(methylamino)-1-phenyl- [ACD/Index Name] 2-(Methylamino)-1-phenyl-1-pentanon [German] [ACD/IUPAC Name] 2-(Methylamino)-1-phenyl-1-pentanone [ACD/IUPAC Name] 2-(Méthylamino)-1-phényl-1-pentanone [French] [ACD/IUPAC Name] Pentedrone [Wiki] 2-(methylamino)-1-phenylpentan-1-one
879722-57-3 [RN] α-methylaminovalerophenone
α-methylamino-valerophenone
879669-95-1 [RN] MFCD20663738

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